Somatic Mosaicism across Human Tissues Data Portal

A platform to search, visualize, and download somatic mosaic variants in normal tissues.

Latest Official Release:

Benchmarking - with all technologies

CellLines

Assays

Mutations

FilesGenerated

Production - with core + additional technologies

CELL LINES & TISSUES

Ectoderm Tissues
  • Brain: unrelated donors iconBrain: unrelated donors
  • Sun-exposed skin iconSun-exposed skin
Endoderm Tissues
  • Liver iconLiver
  • Lung iconLung
  • Colon iconColon
Cell Line Mixtures
  • COLO829 Mixture iconCOLO829 Mixture
  • HapMap Mixture iconHapMap Mixture
  • iPSC & Fibroblast iconiPSC & Fibroblast
Human figure diagram

AVAILABLE ASSAYS

Bulk WGS short read
  • Illumina NovaSeq
  • Ultima Genomics
Bulk WGS long read
  • PacBio HiFi
  • ONT
Bulk RNA-seq
  • Illumina NovaSeq
  • MAS-Seq
Single-cell WGS
  • DLP+
  • MALBAC
  • PTA and PTA-HAT-Seq
  • Cas9-targeted seq
Single-cell RNA-Seq
  • snRNA-Seq
  • STORM-Seq
  • Tranquil-Seq
Single-molecule/duplex WGS
  • Nanoseq
  • CODEC
  • Duplex sequencing
  • HiDEF-Seq
  • CompDuplex-Seq
Epigenome profiling
  • NT-Seq
  • Fiber-Seq
  • Hi-C
  • GoTchA
  • ATAC-Seq/MetaCS

New Data Releases

Announcements

New Access RegulationMar 30, 2026
Due to new data access regulations, all SMaHT Data Portal users MUST use an institutional email address to login to the Data Portal.

Gmail, yahoo, hotmail, and other free email accounts will be prohibited from accessing the Data Portal effective 4/1/26.